Hair Analysis in Clinical and Forensic Toxicology

Pascal KINTZ, Alberto Salomone, Marco Vincentti

 

Editeur : Elsevier

Prix Indicatif : 61.16€ (15% de réduction chez Elsevier)

Nombre de pages : 392

Date de Parution : 21 Août 2015

En langue anglaise

 

Hair Analysis in Clinical and Forensic Toxicology Reviewed by on . L'ouvrage de Référence par excellence, co-rédigé par notre expert national Pascal KINTZ ! Toutes les méthodes de pointe sont clairement expliquées, ainsi que tous les protocoles d'analyses et d'échantillonnage. Le cheveux sous toutes ses coutures : PARFAIT, juste parfait !   .
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L'ouvrage de Référence par excellence, co-rédigé par notre expert national Pascal KINTZ ! Toutes les méthodes de pointe sont clairement expliquées, ainsi que tous les protocoles d'analyses et d'échantillonnage. Le cheveux sous toutes ses coutures : PARFAIT, juste parfait !   .
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A posséder absolument !
Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation

Table des matières :

Hair Analysis in Clinical and Forensic Toxicology, 1st Edition

  • Foreword
  • List of Contributors
  • Chapter 1. Anatomy and Physiology of Hair, and Principles for its Collection1.1
  • Introduction
  • 1.2 Hair Anatomy and Physiology
  • 1.3 Classification of Hair Types
  • 1.4 Hair Growth Rates
  • 1.5 Hair Color
  • 1.6 Mechanisms of Drug Incorporation
  • 1.7 Incorporation from the Bloodstream, Sebum and Sweat
  • 1.8 Incorporation from External Contamination
  • 1.9 Dose-Response Relationship
  • 1.10 Melanin Binding
  • 1.11 Sample Collection Protocols
  • 1.12 Collection Procedure
  • 1.13 Discussion
  • 1.14 Conclusion
  • References
  • Chapter 2. Hair Sample Preparation, Extraction, and Screening Procedures for
  • Drugs of Abuse and Pharmaceuticals
  • 2.1 Introduction
  • 2.2 Sample Preparation
  • 2.3 Analyte Extraction
  • 2.4 Screening Strategies
  • 2.5 Concluding Remarks
  • References
  • Chapter 3. External Contamination: Still a Debate?
  • 3.1 Introduction
  • 3.2 External Contamination: Commonly Encountered Drugs
  • 3.3 Alcohol: FAEE and EtG
  • 3.4 Concluding Remarks
  • References
  • Chapter 4. Alcohol Biomarkers in Hair
  • 4.1 Introduction
  • 4.2 Alcohol Amount, Drinking Pattern, and Minor Metabolites of Ethanol in Hair
  • 4.3 Ethyl Glucuronide
  • 4.4 Fatty Acid Ethyl Esters
  • 4.5 Combined Use of EtG and FAEEs
  • 4.6 Comparison of EtG and FAEE in Hair with Other Alcohol Markers
  • 4.7 Practical Applications of EtG and FAEE in Hair
  • 4.8 Cocaethylene
  • 4.9 Outlook
  • References
  • Chapter 5. Clinical Applications of Hair Analysis
  • 5.1 Introduction
  • 5.2 Hair Analysis in Maternal, Neonatal, and Child Health
  • 5.3 Clinical Applications of Hair Cortisol Analysis
  • 5.4 Future Clinical Applications of Hair Testing
  • References
  • Chapter 6. Experiences in Child Hair Analysis6.1 Introduction
  • 6.2 Age as a Factor of Influence of Drug Distribution
  • 6.3 Differences in Children’s Hair versus Adults
  • 6.4 Case Reports
  • 6.5 Conclusion and Perspectives
  • References
  • Chapter 7. Hair Analysis for the Biomonitoring of Human Exposure to Organic
  • Pollutants7.1 Introduction
  • 7.2 The Challenge of Assessing Environmental Exposure
  • 7.3 Sample Pretreatment
  • References
  • Chapter 8. Workplace Drug Testing
  • 8.1 Introduction
  • 8.2 Ideal Matrix in the Workplace Scenario
  • 8.3 Evidence that a Hair Drug Test Detects More Users than Urine
  • 8.4 Procedures for Drug Testing Using Hair
  • 8.5 Accreditation
  • 8.6 Interpretation and Reporting
  • 8.7 Hair Analysis in the Workplace
  • 8.8 Conclusions
  • References
  • Chapter 9. Forensic Applications of Hair Analysis
  • 9.1 Introduction
  • 9.2 Advantages of Hair Analysis
  • 9.3 Limitations of Hair Analysis 9.4 Applications of Hair Analysis in Forensic Toxicology
  • References
  • Chapter 10. Doping, Applications of Hair Analysis
  • 10.1 Introduction 10.2 Hair Testing for Positive Identification of Prohibited Substances
  • 10.3 Hair Testing as Additional Evidence in Presumptive Doping Cases
  • 10.4 Hair Testing for Doping Control in Animals
  • References
  • Chapter 11. Detection of New Psychoactive Substances
  • 11.1 Introduction 11.2 The Challenge of NPS Detection
  • 11.3 Ketamine
  • 11.4 Synthetic Cathinones
  • 11.5 Synthetic Cannabinoids
  • 11.6 Conclusions
  • Acknowledgments
  • References
  • Chapter 12. New Challenges and Perspectives in Hair Analysis
  • 12.1 Introduction
  • 12.2 Conditioning Factors and Sources of Variability
  • 12.3 Innovative Technologies and Instrumental Advancements
  • References
  • Index

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